TY - JOUR AU - Nygaard, Hanne PY - 2019/04/30 Y2 - 2024/03/28 TI - Comparison Between Frailty Phenotype and Deficit Accumulation – Association with post-discharge 90-day mortality JF - Dansk Tidsskrift for Akutmedicin JA - AKUT VL - 2 IS - 3 SE - Konferenceabstract DO - 10.7146/akut.v2i3.112987 UR - https://tidsskrift.dk/akut/article/view/112987 SP - 45 AB - <p><strong>Background</strong>: Frailty is a clinical syndrome, which develops because of age-related decline, diseases, malnutrition and lifestyle. The syndrome leads to increased vulnerability, decline in physiological reserve and a reduced ability to resist stressors and thus, is associated with death, nursing home admission and prolonged hospital admission.&nbsp;&nbsp; There are two major overall perspectives on frailty; frailty as a phenotype and frailty as an accumulation of deficits. Following this, two different validated screening tools exists; Frieds Phenotype (FP) and Clinical Frailty Scale (CFS). However, the screening tools have not been tested in a Scandinavian cohort.&nbsp; The aim of this study was to investigate the association between frailty defined by FP or CFS, respectively and 90-day mortality in a Danish cohort.</p><p><strong>Methods</strong>: The study was based on the CriSTAL-study (Criteria for Screening and Triaging to Appropriate aLternative care). The cohort was defined as Danish participants age &gt; 65 years, acutely admitted to the ED and subsequent admission longer than 24 hours at Bispebjerg Hospital (BSP), Odense University Hospital (OUH) or Hospital of Southwest Jutland (SVS), respectively. A total of N=1030 were included, equally distributed from each hospital.&nbsp; Frailty was measured at admission to ED. Participants were classified as frail when scoring ≥ 3 by FP or ≥ 5 by CFS. The relative risk (RR) was calculated with a 95% confidence interval (CI) for both FP and CFS. The 90-day mortality were collected using the Danish Death Register.</p><p><strong>Results</strong>: Fifty-four percent (54 %) of the participants were female and mean age was 78.2 years (range: 65-100). Two hundred twenty-one (n=221) and n=555 participants were categorized as frail by FP and CFS, respectively and n=128 died within 90 days.&nbsp;&nbsp;The analyses revealed significant associations between frailty and 90-day mortality; RR=2.67 (95% CI: 1.93-3.69), p &lt; 0.001 and RR=4.12 (95% CI: 2.65-6.42), p &lt; 0.001 with FP and CFS, respectively.</p><p><strong>Conclusion</strong>: There is a significant association between frailty and 90-day mortality in the Danish cohort. However, CFS is a better predictor of <br>90-day mortality compared to FP.</p> ER -